BDBM50514414 CHEMBL4439829

SMILES COC(=O)c1nonc1NCn1cnnn1

InChI Key InChIKey=JLMKTNVLZSGSMC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514414   

TargetSignal transducer and activator of transcription 5B(Human)
Univ. Lille

Curated by ChEMBL

LigandBDBM50514414(CHEMBL4439829)Copy SMILESCopy InChI

Affinity DataIC50: 3.70E+4nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetSignal transducer and activator of transcription 5B(Mouse)
Univ. Lille

Curated by ChEMBL

LigandBDBM50514414(CHEMBL4439829)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL