BDBM50514308 CHEMBL4448899

SMILES Cc1c(NC(=O)c2cc(nc3cc(F)ccc23)C(N)=O)c(nn1Cc1ccc(cc1)C#N)C(F)(F)F

InChI Key InChIKey=BKLJDIJJOOQUFG-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50514308   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 2nMAssay Description:Inhibition of human GLUT1 expressed in DLD1 cells assessed as glucose uptake by measuring ATP incubated for 15 mins by CellTiter-Glo Luminescent Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 50nMAssay Description:Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 1.08E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 1.67E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 290nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50514308(CHEMBL4448899)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed