BDBM50514121 CHEMBL4442615

SMILES c1cc(c(cc1COc2ccc(cc2CNCCO)Br)C(F)(F)F)F

InChI Key InChIKey=ITHSFXDGKQYOED-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514121   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514121(CHEMBL4442615)
Affinity DataIC50: 600nMAssay Description:Inhibition of USP28 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514121(CHEMBL4442615)
Affinity DataIC50: 700nMAssay Description:Inhibition of USP28 (unknown origin) using Ub-Rho100 as substrate by calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50514121(CHEMBL4442615)
Affinity DataIC50: 620nMAssay Description:Inhibition of USP25 (unknown origin) using Ub-Rho100 as substrate by calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed