BDBM50514108 CHEMBL4458116

SMILES [H][C@]12C[C@@]3([H])C[C@@H](C[C@H](C)N3C[C@@]1(C[C@]1(C(=O)Nc3c1cccc3C(=O)[C@H]1OC1(C)C)[C@]2(C)C=O)NC)OC(=O)CCCC

InChI Key InChIKey=ZSVWJJBSLMNNAT-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514108   

TargetHistamine H3 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50514108(CHEMBL4458116)
Affinity DataEC50:  126nMAssay Description:Agonist activity at recombinant human H3R expressed on cells incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50514108(CHEMBL4458116)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells incubated for 40 min by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed