BDBM50514058 CHEMBL4458929

SMILES CCOc1ccc(Cc2nc3cc(ccc3n2CCCNc2c3CCCCc3nc3ccccc23)C(=O)N(CC)CC)cc1

InChI Key InChIKey=ZVJIYGXYCVEXOA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514058   

TargetAcetylcholinesterase(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50514058(CHEMBL4458929)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50514058(CHEMBL4458929)
Affinity DataIC50: 501nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50514058(CHEMBL4458929)
Affinity DataKi:  3.07E+4nMAssay Description:Displacement of [3H]-CP55940 from human recombinant cannabinoid CB2 receptor expressed in human HEK cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed