BDBM50513743 CHEMBL4438605

SMILES COc1cc2CCN(CCCOc3ccc(C(C)=O)c(O)c3)Cc2cc1OC

InChI Key InChIKey=UGTOHDDXGFCAEE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50513743   

TargetAcetylcholinesterase(Electric eel)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50513743(CHEMBL4438605)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide incubated for 15 mins as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50513743(CHEMBL4438605)
Affinity DataIC50: 5.79E+4nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine chloride as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50513743(CHEMBL4438605)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine as substrate measured after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50513743(CHEMBL4438605)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human MAO-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50513743(CHEMBL4438605)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of recombinant human MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed