BDBM505136 US11066409, Compound I-0154

SMILES CCc1nc(OC)ccc1NC1=NC(=O)N(C)C2=NCC(N12)c1cc(F)c(F)c(F)c1

InChI Key InChIKey=YULSDWJBSWOUGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 505136   

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505136(US11066409, Compound I-0154)
Affinity DataIC50: 17nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
Go to US Patent