BDBM50513351 CHEMBL4516101

SMILES FC(F)(F)c1cc(CN2CCCC2)cc(c1)C1CCN(CCc2cnn(c2)-c2nccc3c2nc[nH]c3=O)CC1

InChI Key InChIKey=LAGKZFNQXIBSDJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50513351   

TargetLysine-specific demethylase 2A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of KDM2A (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 71nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5C(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 38nMAssay Description:Inhibition of KDM5C (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 3A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of KDM3A (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of KDM6B (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 17nMAssay Description:Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed