BDBM50513256 CHEMBL4442995

SMILES CCOc1cc(O)cc2O[C@@H]([C@@H](Cc12)OC(=O)c1cc(OCC)c(OCC)c(OCC)c1)c1cc(O)c(OCC)c(OCC)c1

InChI Key InChIKey=QNYUPQMBRWBCFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513256   

TargetATP-dependent translocase ABCB1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50513256(CHEMBL4442995)
Affinity DataIC50: 620nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 1 uM incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50513256(CHEMBL4442995)
Affinity DataIC50: 920nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 2 uM incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed