BDBM50513227 CHEMBL4547969

SMILES COc1ccc(CN[C@H](C)c2nc3n(ncc3c(=O)[nH]2)C2CCCC2)c(O)c1

InChI Key InChIKey=DPPSRHLQBYNNJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513227   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513227(CHEMBL4547969)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of PDE9 catalytic domain (unknown origin) using [3H]cAMP or [3H]cGMP as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513227(CHEMBL4547969)
Affinity DataIC50: 34nMAssay Description:Inhibition of PDE9 (unknown origin) using 3[H]-cGMP as substrate incubated for 15 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed