BDBM50513065 CHEMBL4443601

SMILES O=c1n(-c2ccccc2)c(nn2cccc12)[C@@H]1CCCN1c1ncnc2[nH]cnc12

InChI Key InChIKey=SROFVJBCNYOZIX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513065   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hutchison Medipharma

Curated by ChEMBL

LigandBDBM50513065(CHEMBL4443601)Copy SMILESCopy InChI

Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human full-length His-tagged PI3K p110gamma expressed in baculovirus expression system using PIP2 as substrate measured aft...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hutchison Medipharma

Curated by ChEMBL

LigandBDBM50513065(CHEMBL4443601)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL