BDBM505130 US11066409, Compound I-0107::US11066409, Compound I-0111

SMILES CCN1C2=NCC(N2C(Nc2cc(C)c(C)cc2C)=NC1=O)c1ccccc1

InChI Key InChIKey=DURPTYYCGPVFOA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 505130   

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505130(US11066409, Compound I-0111 | US11066409, Compound...)
Affinity DataIC50: 25nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505130(US11066409, Compound I-0111 | US11066409, Compound...)
Affinity DataIC50: 10nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505130(US11066409, Compound I-0111 | US11066409, Compound...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed