BDBM50512875 CHEMBL4567071

SMILES C[C@H](Nc1ncnc2[nH]cc(-c3ccc(O)c(CN4CCC(CC4)N(C)C)c3)c12)c1nn2ccc(C)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=RTJKOLIMBPYBJS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512875   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50512875(CHEMBL4567071)Copy SMILESCopy InChI

Affinity DataIC50: 0.430nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL