BDBM50512840 CHEMBL4590126

SMILES Fc1cnc(Nc2ccc(OCCSC(=S)NCc3ccc(cc3)C#N)cc2)nc1Nc1cccc(NC(=O)C=C)c1

InChI Key InChIKey=ZGJVASMUMZLZTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512840   

TargetTyrosine-protein kinase BTK(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50512840(CHEMBL4590126)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human recombinant full length BTK expressed in baculovirus in Sf9 insect cells using Poly (4:1 Glu, Tyr) as substrate incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed