BDBM50512789 CHEMBL4583609

SMILES Clc1cc(Cl)cc(c1)N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccsc2)CC1

InChI Key InChIKey=DQOGQIXFWPGESA-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50512789   

TargetCytochrome P450 2D6(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512789(CHEMBL4583609)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512789(CHEMBL4583609)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512789(CHEMBL4583609)
Affinity DataKi:  0.440nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D3 receptor expressed in HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512789(CHEMBL4583609)
Affinity DataKi:  2.05E+3nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D2L receptor expressed in HEK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512789(CHEMBL4583609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from dopamine D1 receptor (unknown origin) expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512789(CHEMBL4583609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from dopamine D5 receptor (unknown origin) expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512789(CHEMBL4583609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from dopamine human D4 receptor expressed in HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed