BDBM50512717 CHEMBL4435689

SMILES CC[C@@H](CC(O)=O)c1cccc(NC(=O)C(C2CCCC2)c2ccc(cc2)-c2cncc(CC)c2)c1C

InChI Key InChIKey=YCZXGDRTZAULOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512717   

TargetProstaglandin E synthase(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50512717(CHEMBL4435689)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProstaglandin E synthase(Mouse)
Bayer

Curated by ChEMBL
LigandPNGBDBM50512717(CHEMBL4435689)
Affinity DataIC50: 203nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed