BDBM50512566 CHEMBL4444708

SMILES COc6ccc5[se]n(CCCCCCn4[se]c3ccc(OCCCCC[C@@H]2SCC1NC(=O)NC12)cc3c4=O)c(=O)c5c6

InChI Key InChIKey=URPCJZKVOUNFJB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512566   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50512566(CHEMBL4444708)
Affinity DataIC50: 73nMAssay Description:Allosteric inhibition of human KGA assessed as reduction in glutamate formation using glutamine as substrate pretreated with enzyme for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50512566(CHEMBL4444708)
Affinity DataKd:  142nMAssay Description:Binding affinity to human KGA assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed