BDBM50512564 CHEMBL4594058

SMILES Brc1ccccc1C(=O)Nc1cccc(NC(=O)c2cocn2)c1

InChI Key InChIKey=LNBNAKYSTOHIEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512564   

TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50512564(CHEMBL4594058)
Affinity DataIC50: 420nMAssay Description:Negative allosteric modulation of PAR1 in human EAhy926 cells assessed as reduction in TFLLRN-NH2-induced intracellular calcium mobilization incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50512564(CHEMBL4594058)
Affinity DataIC50: 398nMAssay Description:Negative allosteric modulation of PAR1 in human EAhy926 cells assessed as reduction in TFLLRN-NH2-induced intracellular calcium mobilization incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed