BDBM50512262 CHEMBL4589103

SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cc3)N3CCNCC3)nc2n1C1CCCC1

InChI Key InChIKey=GIEZCFPNBLPSOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50512262   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50512262(CHEMBL4589103)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK4/CyclinD1 (unknown origin) assessed as reduction in retinoblastoma phosphorylation at S473 residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50512262(CHEMBL4589103)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CDK2/CyclinA (unknown origin) assessed as reduction in TAMRA tagged peptide substrate phosphorylation by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50512262(CHEMBL4589103)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed