BDBM50512161 CHEMBL4472378

SMILES O=C(N\N=C\c1ccccc1)C(N1C(=O)c2ccccc2S1(=O)=O)C(=O)N\N=C\c1ccccc1

InChI Key InChIKey=MJTAIJKIQBWBCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512161   

TargetProstaglandin G/H synthase 1(Sheep)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50512161(CHEMBL4472378)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in oxidized TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50512161(CHEMBL4472378)
Affinity DataIC50: 290nMAssay Description:Inhibition of ovine COX2 assessed as reduction in oxidized TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed