BDBM50512155 CHEMBL4582722

SMILES Cc1cc(-c2ccccc2)n(n1)C(=O)C(N1C(=O)c2ccccc2S1(=O)=O)C(=O)n1nc(C)cc1-c1ccccc1

InChI Key InChIKey=SETSXTRBUALZTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512155   

TargetProstaglandin G/H synthase 2(Sheep)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50512155(CHEMBL4582722)
Affinity DataIC50: 50nMAssay Description:Inhibition of ovine COX2 assessed as reduction in oxidized TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50512155(CHEMBL4582722)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in oxidized TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed