BDBM50511930 CHEMBL4584344

SMILES COCCNS(=O)(=O)c1ccc(Nc2ncc(cn2)-c2cnc3cccnn23)cc1

InChI Key InChIKey=NVXCHWIKSUXHPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50511930   

TargetCyclin-dependent kinase 1(Human)
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511930(CHEMBL4584344)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of South Australia Cancer Research Institute

Curated by ChEMBL
LigandPNGBDBM50511930(CHEMBL4584344)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human CDK2/cyclin E expressed in baculovirus infected Sf21 insect cells using GST-tagged Rb protein (792 to 928 residues) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed