BDBM50511920 CHEMBL4546176

SMILES CN(Cc1ccc(cc1)-n1cnn(CCCCc2ccc(cc2)C(=O)NO)c1=O)CC(O)(Cn1cncn1)c1ccc(F)cc1F

InChI Key InChIKey=QFLKHNDDHKDKQQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511920   

TargetHistone deacetylase 6(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511920(CHEMBL4546176)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC6 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511920(CHEMBL4546176)
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC1 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511920(CHEMBL4546176)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed