BDBM50511919 CHEMBL4562449

SMILES CN(Cc1ccc(OCCCOc2ccc(CC(=O)NO)cc2)cc1)CC(O)(Cn1cncn1)c1ccc(F)cc1F

InChI Key InChIKey=UVYCRTBNTSJPHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511919   

TargetHistone deacetylase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511919(CHEMBL4562449)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511919(CHEMBL4562449)
Affinity DataIC50: 690nMAssay Description:Inhibition of HDAC1 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50511919(CHEMBL4562449)
Affinity DataIC50: 600nMAssay Description:Inhibition of HDAC6 (unknown origin) after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed