BDBM50511728 CHEMBL4577396

SMILES [H][C@@]1(c2ccccc2-c2cncn12)[C@]1([H])CCc2ccccc2[C@H]1O

InChI Key InChIKey=VKUCRVDZHQWVKF-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511728   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50511728(CHEMBL4577396)
Affinity DataEC50:  240nMAssay Description:Inhibition of IDO1 in human A172 cells after 24 hrs in presence of IFNgamma by NFK green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50511728(CHEMBL4577396)
Affinity DataIC50: 840nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50511728(CHEMBL4577396)
Affinity DataEC50:  32nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed