BDBM50511576 CHEMBL4537045

SMILES [H][C@]1(O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@]3([H])[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](OCCNS([O-])(=O)=O)O[C@@H]3COS([O-])(=O)=O)O[C@@H]2C([O-])=O)O[C@H](COS([O-])(=O)=O)[C@@H](O)[C@H](O)[C@H]1NS([O-])(=O)=O

InChI Key InChIKey=FDSRZUAKMKTBCH-UHFFFAOYSA-H

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511576   

TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataIC50: 393nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of coagulation factor 2a (unknown origin) incubated for 2 mins in presence of AT3 by chromogenic substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPlatelet factor 4(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to PF4 (unknown origin) by BLI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of coagulation factor 10a (unknown origin) incubated for 2 mins in presence of AT3 by chromogenic substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed