BDBM50511511 CHEMBL4437552

SMILES [H][C@]12Cc3cc(CC)c(OC(C)=O)c(OC(C)=O)c3-c3cccc(CCN1C)c23

InChI Key InChIKey=BWRISDCHRCNQPM-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50511511   

TargetD(2) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  1.62E+3nMAssay Description:Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  1.55E+3nMAssay Description:Agonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  3.59E+3nMAssay Description:Agonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  1.55E+3nMAssay Description:Agonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50511511(CHEMBL4437552)
Affinity DataEC50:  3.55E+3nMAssay Description:Agonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed