BDBM50511335 CHEMBL4439245

SMILES Fc1ccc2c(CNC(=O)Cc3ccc(Oc4nc5ccccc5s4)cc3F)c[nH]c2c1

InChI Key InChIKey=URDNGEHEARGIJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50511335   

TargetBifunctional epoxide hydrolase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50511335(CHEMBL4439245)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50511335(CHEMBL4439245)
Affinity DataIC50: 900nMAssay Description:Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed