BDBM50511248 CHEMBL4581033

SMILES Cc1noc(C)c1-c1nc2sc3CN(CC(=O)Nc4ccccc4N)CCc3c2c(=O)[nH]1

InChI Key InChIKey=XGOHVFIQCCFBCJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511248   

TargetHistone deacetylase 2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511248(CHEMBL4581033)
Affinity DataIC50: 352nMAssay Description:Inhibition of HDAC2 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511248(CHEMBL4581033)
Affinity DataIC50: 391nMAssay Description:Inhibition of HDAC6 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511248(CHEMBL4581033)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50511248(CHEMBL4581033)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed