BDBM50510850 CHEMBL4552675

SMILES COc1ccc2nc3CCCCc3c(NCCCCCCCCN(CC(=O)Nc3ccc4ccccc4c3)C(=O)\C=C\c3ccc(O)c(OC)c3)c2c1

InChI Key InChIKey=CIMNCRAYKQYYMB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510850   

TargetCholinesterase(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510850(CHEMBL4552675)
Affinity DataIC50: 68nMAssay Description:Inhibition of human serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50510850(CHEMBL4552675)
Affinity DataIC50: 22nMAssay Description:Inhibition of human AchE preincubated for 20 mins followed by substrate addition using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510850(CHEMBL4552675)
Affinity DataIC50: 68nMAssay Description:Inhibition of human BuchE preincubated for 20 mins followed by substrate addition using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed