BDBM50510844 CHEMBL4451532

SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(NCCNc2c3CCCCc3nc3cc(Cl)ccc23)cc1

InChI Key InChIKey=CHMUJRNDDRQZFR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50510844   

TargetAcetylcholinesterase(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510844(CHEMBL4451532)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510844(CHEMBL4451532)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human plasma butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510844(CHEMBL4451532)
Affinity DataIC50: 4.73E+3nMAssay Description:Inhibition of human AChE by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510844(CHEMBL4451532)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of AChE in human erythrocytes preincubated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed