BDBM50510822 CHEMBL4526395

SMILES [H][C@@]12CN(C[C@@]1(N=C(N)SC2)c1cc(NC(=O)c2cnc(OC)cn2)ccn1)c1ncc(F)cn1

InChI Key InChIKey=IIMOLGKMCNSOEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510822   

TargetBeta-secretase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50510822(CHEMBL4526395)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells after 16 to 24 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed