BDBM50510788 CHEMBL4576365

SMILES [H][C@]12CSC(N)=N[C@]1(CCO2)c1cccc(NC(=O)c2cnc(cn2)C(F)F)c1

InChI Key InChIKey=RVBIOGZPASVJHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510788   

TargetBeta-secretase 1(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50510788(CHEMBL4576365)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in Wistar rat neuronal cell suspension after 1 to 3 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed