BDBM50510771 CHEMBL4467035

SMILES [H][C@]12CSC(N)=N[C@]1(CO[C@@H]2C(F)F)c1cc(NC(=O)c2cnc(OC)cn2)ccc1F

InChI Key InChIKey=FPVZNUAOWBQSIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510771   

TargetBeta-secretase 1(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50510771(CHEMBL4467035)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 in Wistar rat neuronal cell suspension after 1 to 3 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed