BDBM50510763 CHEMBL2218927

SMILES Cc1nc2cc3nc(cnc3cc2n1C)-c1cccs1

InChI Key InChIKey=ZGDACLBJJXLKJY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50510763   

LigandPNGBDBM50510763(CHEMBL2218927)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human FLT3 expressed in mouse BAF3 cells assessed as reduction in tyrphostin activity incubated for 2 hrs followed by FLT3 ligand stimu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
India

Curated by ChEMBL
LigandPNGBDBM50510763(CHEMBL2218927)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EGFR in human A431 cells incubated for 2 hrs followed by EGF stimulation and measured after 10 mins by immunoblot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
India

Curated by ChEMBL
LigandPNGBDBM50510763(CHEMBL2218927)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IGFR1 (unknown origin) using poly (Glu,Tyr) 4:1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50510763(CHEMBL2218927)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SRC in transformed mouse NIH3T3 cells by SDS-PAGE based immunoblot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50510763(CHEMBL2218927)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-KIT in human M-07e cells assessed as reduction in tyrphostin activity incubated for 2 hrs followed by KIT ligand stimulation by immun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50510763(CHEMBL2218927)
Affinity DataIC50: 90nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed