BDBM50510627 CHEMBL4587609

SMILES COc1cccc(F)c1-c1ccccc1C=NOCCN1CCC(C1)C(O)=O

InChI Key InChIKey=GKHIAOHGTDTCNS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510627   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50510627(CHEMBL4587609)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50510627(CHEMBL4587609)
Affinity DataKi:  407nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed