BDBM50510569 CHEMBL4533153

SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key InChIKey=OPMJBWVXRQIVBZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50510569   

TargetALK tyrosine kinase receptor(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 400nMAssay Description:Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 375nMAssay Description:Inhibition of RON (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 95nMAssay Description:Inhibition of KDR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 418nMAssay Description:Inhibition of FLT1 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 356nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 380nMAssay Description:Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
School of Marine Science and Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: 242nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed