BDBM50510281 CHEMBL4565072::US10711036, Compound 205

SMILES CN[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF

InChI Key InChIKey=XFSAHYSRADWIEC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510281   

LigandPNGBDBM50510281(CHEMBL4565072 | US10711036, Compound 205)
Affinity DataKi: >200nMAssay Description:Inhibition of recombinant LZ-fused MALT1 (340 to 789 residues) (unknown origin) using Ac-LRSR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50510281(CHEMBL4565072 | US10711036, Compound 205)
Affinity DataKi: >200nMAssay Description:For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2021
Entry Details
Go to US Patent