BDBM50510038 CHEMBL4518161

SMILES Cc1nn(c(C)c1-c1ccc(F)cc1)-c1ccc(CN)cc1

InChI Key InChIKey=BBLWVUFVBPWMEM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50510038   

LigandPNGBDBM50510038(CHEMBL4518161)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG incubated for 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid-sensing ion channel 2(Mouse)
Promidis

Curated by ChEMBL
LigandPNGBDBM50510038(CHEMBL4518161)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of pH 5.5-stimulated mouse ASIC2a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Mouse)
Promidis

Curated by ChEMBL
LigandPNGBDBM50510038(CHEMBL4518161)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid-sensing ion channel 2(Mouse)
Promidis

Curated by ChEMBL
LigandPNGBDBM50510038(CHEMBL4518161)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Promidis

Curated by ChEMBL
LigandPNGBDBM50510038(CHEMBL4518161)
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP1A2 (unknown origin) using pro-luciferin substrates in presence of NADPH by firefly luciferase reporter gene based P450-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed