BDBM50509997 CHEMBL4527356

SMILES OCc1ccc(CNC(=O)c2c[nH]c3ccc(Cl)cc23)cc1

InChI Key InChIKey=TVWGXVODHUOYHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509997   

TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509997(CHEMBL4527356)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509997(CHEMBL4527356)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509997(CHEMBL4527356)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed