BDBM50509991 CHEMBL4539177

SMILES OCc1ccc(NC(=O)c2[nH]c3ccc(Cl)cc3c2Cc2ccccc2)cc1

InChI Key InChIKey=FHIRYPMBXVLHTD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509991   

TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509991(CHEMBL4539177)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509991(CHEMBL4539177)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509991(CHEMBL4539177)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed