BDBM50509895 CHEMBL4538857::US20230340011, Example 153.

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)N(C)CC

InChI Key InChIKey=UIVYMANQVISZNZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509895   

TargetOxysterols receptor LXR-beta(Rat)
Niigata University of Pharmacy and Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50509895(CHEMBL4538857 | US20230340011, Example 153.)
Affinity DataEC50:  786nMAssay Description:Transactivation of rat LXRbeta expressed in HEK293FT cells measured after 14 to 18 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Asteroid Therapeutics

US Patent
LigandPNGBDBM50509895(CHEMBL4538857 | US20230340011, Example 153.)
Affinity DataIC50: 125nMAssay Description:10,000 cells/well of the PathHunter U2OS SREBP-2 Nuclear Translocation Cell Line are plated in quadruplicate on 384 well plates in 20 μL of Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetOxysterols receptor LXR-beta(Human)
Asteroid Therapeutics

US Patent
LigandPNGBDBM50509895(CHEMBL4538857 | US20230340011, Example 153.)
Affinity DataIC50: 625nMAssay Description:PathHunter NHR CHO cells stably transfected with tagged full-length human LXRβ and a nuclear fusion protein containing Steroid Receptor Co-activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent