BDBM50509771 CHEMBL4467986

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(\[#6]=[#6]\[#6](-[#8])=O)cc(c1)-[#6](=O)-[#7]-[#6]-c1ccc(-[#6])cc1

InChI Key InChIKey=RLGAPXOYZGQYTF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50509771   

TargetAldo-keto reductase family 1 member C4(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509771(CHEMBL4467986)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of recombinant human AKR1C4 expressed in Escherichia coli BL21 (D3) using S-tetralol as substrate in presence of NADP+ by UV-spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509771(CHEMBL4467986)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human AKR1C3 expressed in Escherichia coli BL21 (D3) using S-tetralol as substrate in presence of NADP+ by UV-spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509771(CHEMBL4467986)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50509771(CHEMBL4467986)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant AKR1C1 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50509771(CHEMBL4467986)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509771(CHEMBL4467986)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of recombinant AKR1C4 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed