BDBM50509767 CHEMBL4513510

SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC(C)(C)O)CC1

InChI Key InChIKey=OXSCPDKUZWPWFR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50509767   

TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human AKR1C3 expressed in Escherichia coli BL21 measured after 1.5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-R1881 from androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 incubated for 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 290nMAssay Description:Inhibition of human AKR1C3 using 4-AD as substrate in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 in presence of DHT by BrightG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 assessed as reduction in NADPH-dependent 9,10-phenanthrenequinone convers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human AKR1C2 transfected in Escherichia coli BL21 assessed as reduction in NADPH-dependent 9,10-phenanthrenequinone convers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50: 10nMAssay Description:Inhibition of human AKR1C3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed