BDBM50509750 CHEMBL4439327

SMILES Oc1ccc2c(O)ncc(-c3cc(F)c(F)c(F)c3)c2c1

InChI Key InChIKey=CMNAKAUBHYLUQT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50509750   

TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509750(CHEMBL4439327)
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant human AKR1C3 expressed in Escherichia coli BL21 measured after 1.5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509750(CHEMBL4439327)
Affinity DataIC50: 8.00E+4nMAssay Description:Displacement of [3H]-R1881 from androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 incubated for 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50509750(CHEMBL4439327)
Affinity DataIC50: 35nMAssay Description:Inhibition of human AKR1C3 using S-tetralol as substrate in presence of NADP by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509750(CHEMBL4439327)
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 in presence of DHT by BrightG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed