BDBM50509704 CHEMBL4443988

SMILES Clc1ccc(cc1)-n1cc(COc2ccc(C=NNc3c4CCCCc4nc4ccccc34)cc2)nn1

InChI Key InChIKey=MZMUBKIIIBTNQJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50509704   

TargetProstaglandin G/H synthase 2(Sheep)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509704(CHEMBL4443988)
Affinity DataIC50: 43nMAssay Description:Inhibition of ovine COX -2 by colorimetric inhibitor screening assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509704(CHEMBL4443988)
Affinity DataIC50: 68nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for 180 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509704(CHEMBL4443988)
Affinity DataIC50: 4.38E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 10 mins by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509704(CHEMBL4443988)
Affinity DataIC50: 7.03E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509704(CHEMBL4443988)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of ovine COX -1 by colorimetric inhibitor screening assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed