BDBM50509625 CHEMBL4573030

SMILES CSc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=AIQMUSBBSCOYQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509625   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50509625(CHEMBL4573030)
Affinity DataIC50: 15nMAssay Description:Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50509625(CHEMBL4573030)
Affinity DataIC50: 560nMAssay Description:Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed