BDBM50509607 CHEMBL4465394

SMILES O=C(NC1CCN(CC1)S(=O)(=O)C[C@H]1CC[C@@H](CC1)NCc1ccccc1)c1cc(on1)C1CC1

InChI Key InChIKey=SQGOVOAUUGBLLJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509607   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509607(CHEMBL4465394)
Affinity DataEC50:  22nMAssay Description:Inhibition of recombinant SMYD3 (unknown origin) transfected in human HEK293 cells assessed as reduction in MEKK2 methylation incubated for 24 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509607(CHEMBL4465394)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant N-terminal FLAG/His-tagged SMYD3 (unknown origin) expressed in baculovirus infected insect cells using 3H-SAM as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed