BDBM50509582 CHEMBL4558640

SMILES CN1CCC(CC1)S(=O)(=O)N1CCC(CC1)NC(=O)c1cc(on1)C1CC1

InChI Key InChIKey=DOMSNVMWXMGHSL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509582   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509582(CHEMBL4558640)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant N-terminal FLAG/His-tagged SMYD3 (unknown origin) expressed in baculovirus infected insect cells using 3H-SAM as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509582(CHEMBL4558640)
Affinity DataEC50:  300nMAssay Description:Inhibition of recombinant SMYD3 (unknown origin) transfected in human HEK293 cells assessed as reduction in MEKK2 methylation incubated for 24 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed