BDBM50509502 CHEMBL4442178

SMILES CC(Nc1nc(C)nc2cnc(OCCN(C)C)cc12)c1ccc(s1)-c1ccccc1CN(C)C

InChI Key InChIKey=RWUUTVZPCZBYDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50509502   

TargetEpidermal growth factor receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50509502(CHEMBL4442178)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR phosphorylation at Y 1173 residues in human HeLa cells preincubated for 30 mins followed by EGF-stimulation and measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed